Ivanor™ ইভানর™ ইভাব্রাডিন করোনারি হৃদরোগ (করোনারি আর্টারি ডিজিজ) রোগে আক্রান্ত রোগী যাদের সাইনাসের ছন্দ স্বাভাবিক তাদের ক্ষেত্রেক্রণিক স্ট্যাবল এনজিনার উপসর্গ ভিত্তিক চিকিৎসায় ব্যবহৃত হয়
Ivabradine
Antianginal Drugs (Cardiovascular Preparations)
Indication:
Symptomatic treatment of chronic stable angina pectoris in coronary artery
disease patients with normal sinus rhythm.Ivanor TM is indicated:
-In patients unable to tolerate or with a contra-indication to the use of
beta-blockers, or
- In combination with beta-blockers in patients inadequately controlled with an
optimal beta-blocker dose and whose heart rate is > 60 bpm.
Dosage & Administration:
The usual recommended starting dose of Ivabradine is 5 mg twice daily which may
be increased after 3-4 weeks of treatment to 7.5 mg twice daily, depending on
therapeutic response. Usual dose is 1 tablet in the morning and 1 tablet in the
evening during meals.
If the heart rate decreases persistently below 50 bpm at rest or if symptoms
related to bradycardia, the dose must be adjusted downwards to 2.5mg twice
daily (one half of the 5 mg tablet twice daily). Treatment must be discontinued
if heart rate remains below 50 bpm or symptoms of bradycardia persist. Elderly:
Consider a lower starting dose (2.5 mg twice daily i.e. one half 5 mg tablet
twice daily).
Renal insufficiency: Use with caution in patients with creatinine clearance
less than 15 ml/min.
Hepatic Impairment: Use with caution in patients with moderate hepatic
impairment; contraindicated in severe hepatic impairment.
Children and adolescents: Not recommended.
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Preparation:
Ivanor TM 5 tablet: Each box containing 10 film coated
tablets in Alu-PVDC blister pack.
Ivanor TM 7.5 tablet: Each box containing 10 film coated
tablets in Alu-PVDC blister pack.
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